Lactobacillus brevis

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Lactobacillaceae -> Lactobacillus -> Lactobacillus brevis

OVERVIEW:

Lactobacillus brevis is a gram-positive, rod shaped species of lactic acid bacteria, there are approximately 16 different strains. It can be found in many different environments: fermented foods and as normal microbiota. L.brevis is found in food such as sauerkraut and pickles. It is also one of the most common causes of beer spoilage. Ingestion has been shown to improve human immune function, and it has been patented several times. Normal gut microbiota L.brevis is found in human intestines, vagina and feces. L. brevis uses the glycolysis process to metabolize carbon sources by active transport, which moves material against the concentration gradient, normally this occurs is a movement from a high to low concentration. This pathway is used in probiotics and food preservation. There are significant vaginal bacteria that are found within the vagina and L. brevis is included in this microbiome, which is a collection of various bacteria. The bacteria collaborate on protecting the vagina and vaginal maintenance. Women of childbearing ages have a significant amount of L.brevis and this is normally found in a healthy vagina. For some illnesses or disruptions of the vagina this bacteria can be used in aiding to restore the microbiome. Most of the Lactobacillus species of bacteria have been found useful in preventing urinary tract infections. During normal childbirth, it appears that newborns after a period of days receive transmission of L. brevis from the mother. It appears that the transmission occurs through breast feeding or through natural child birth. In infants, this resistance is also helpful with protecting the gut against various bile and acids. Helicobacter pylori, which is a common gut pathogen in humans, studies have shown that certain strains of L.brevis are successful at combating this pathogen.Vaginosis is the most common form of bacterial infection this is commonly diagnosed as a yeast infection or trichomoniasis, which is a sexually transmitted parasite commonly acquired during intercourse. L.brevis along with Lactobacillus jensenii has been shown to produce high levels of hydrogen peroxide which may be able remediate the bacterial vaginosis pathogenesis. L. Brevis is a commonly used ingredient in pharmaceutical materials used to treat vaginosis. An evaluation of clue cells is one method of assessing vaginosis; this assessment is performed by mounting clue cells and vaginal discharge onto a slide then adding sodium chloride followed by a microscopic assessment which involves bacteria identification. Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Identified as constituent of vaginal microbiome. [PMID:23282177]

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]


Food fermenter
Probiotic
Gut associated
Flora/ commensal
Oral microbiome
Vaginal microbiome
Fecal distribution
Name
Rank
Client %
Avg %
Avg StdDev
Client StdDev
Lactobacillus brevis
species
atypical
atypical
INTERACTIONS

Lactobacillus brevis inhibits growth of
  • Enterococcus
  • Helicobacter pylori
  • Peptoclostridium difficile
  • CLUSTERS WITH
    Group 123
  • Lactobacillus delbrueckii
  • Lactobacillus brevis
  • Group 120
  • Streptococcus thermophilus
  • Lactobacillus brevis
  • Group 7
  • Staphylococcus epidermidis
  • Leuconostoc mesenteroides
  • Lactobacillus acidophilus
  • Lactobacillus plantarum
  • Bacillus cereus
  • Streptococcus thermophilus
  • Listeria monocytogenes
  • Pediococcus pentosaceus
  • Bacteroides fragilis
  • Staphylococcus saprophyticus
  • Clostridium perfringens
  • Listeria innocua
  • Corynebacterium jeikeium
  • Lactobacillus sakei
  • Streptococcus pneumoniae
  • Staphylococcus aureus
  • Streptococcus sanguinis
  • Streptococcus pyogenes
  • Lactobacillus casei
  • Pseudomonas aeruginosa
  • Lactobacillus brevis
  • Enterococcus faecalis
  • Streptococcus agalactiae
  • Fusobacterium nucleatum
  • Lactococcus lactis
  • Streptococcus gordonii
  • Staphylococcus haemolyticus
  • Group 122
  • Lactobacillus salivarius
  • Lactobacillus brevis
  • Group 68
  • Staphylococcus saprophyticus
  • Oenococcus oeni
  • Lactobacillus sakei
  • Lactobacillus brevis
  • Group 2
  • Leuconostoc mesenteroides
  • Lactobacillus salivarius
  • Lactobacillus acidophilus
  • Bifidobacterium adolescentis
  • Lactobacillus plantarum
  • Streptococcus thermophilus
  • Oenococcus oeni
  • Listeria monocytogenes
  • Lactobacillus gasseri
  • Chloroflexus aurantiacus
  • Bacillus pumilus
  • Pediococcus pentosaceus
  • Bacillus licheniformis
  • Listeria innocua
  • Lactobacillus sakei
  • Clostridium acetobutylicum
  • Bifidobacterium longum
  • Lactobacillus johnsonii
  • Lactobacillus brevis
  • Lactococcus lactis
  • Streptococcus gordonii
  • Lactobacillus delbrueckii
  • Group 121
  • Lactobacillus gasseri
  • Lactobacillus brevis
  • Group 15
  • Streptococcus mutans
  • Leuconostoc mesenteroides
  • Lactobacillus salivarius
  • Lactobacillus johnsonii
  • Streptococcus thermophilus
  • Oenococcus oeni
  • Listeria monocytogenes
  • Lactobacillus brevis
  • Hahella chejuensis
  • Pediococcus pentosaceus
  • Listeria innocua
  • Lactobacillus delbrueckii
  • Lactobacillus sakei
  • Group 4
  • Streptococcus mutans
  • Leuconostoc mesenteroides
  • Lactobacillus salivarius
  • Lactobacillus acidophilus
  • Bifidobacterium adolescentis
  • Streptococcus thermophilus
  • Lactobacillus gasseri
  • Pediococcus pentosaceus
  • Clostridium perfringens
  • Listeria innocua
  • Lactobacillus sakei
  • Bifidobacterium longum
  • Lactobacillus johnsonii
  • Streptococcus sanguinis
  • Lactobacillus casei
  • Lactobacillus brevis
  • Streptococcus gordonii
  • Lactobacillus delbrueckii

  • METABOLOMICS   
    Substrates/ Growth Factors
  • Ellagic acid [parent]
  • D-Glucose [parent]
  • CO2 [parent]
  • α-Glucan [parent]

  • Metabolic Endproducts
  • Urolithins [parent]
  • Lactate [parent]
  • Acetylcholine [parent]
  • γ-Amino butyric acid (GABA) [parent]
  • Vitamin B12 [parent]
  • Trimethylamine [parent]
  • Lactic acid [parent]

  • Growth Inhibited by
  • Stevia [parent]
  • Laminaria hyperborea (curvie) [parent]
  • Chemotherapy [parent]
  • Magnesium-deficient diet [parent]
  • Glyphosphate [parent]
  • High fat diet [parent]
  • Sucralose (Splenda) [parent]

  • Growth Enhanced By
  • Sesame cake/meal [parent]
  • Almonds/ almond skins [parent]
  • Navy bean (Cooked) [parent]
  • Magnesium [parent]
  • Daesiho-tang (DSHT) [parent]
  • Resveratrol [parent]
  • Proton-pump inhibitors (PPI) [parent]
  • Laminaria digitata (oarweed) [parent]
  • Melatonin [parent]

  • Biotransforms
  • Linoleic acid (LA) [parent]
  • Linolenic acid (CLnA) [parent]

  • Transform Product
  • 10‐Hydroxy‐cis‐12‐octadecenoate (HYA) [parent]
  • Trans-11 conjugate linoleic acid (CLA) [parent]
  • Cis-9 conjugate linoleic acid (CLA) [parent]
  • Cis-15 conjugate linolenic acids (CLnA) [parent]
  • Cis-9 conjugate linolenic acids (CLnA) [parent]
  • 10-Hydroxyoctadecanoate (HYB) [parent]
  • Trans-11 conjugate linolenic acids (CLnA) [parent]