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Lactobacillus brevisRANK: SpeciesTAXONOMY: Terrabacteria group -> Firmicutes -> Bacilli -> Lactobacillales -> Lactobacillaceae -> Lactobacillus -> Lactobacillus brevis OVERVIEW: Lactobacillus brevis is a gram-positive, rod shaped species of lactic acid bacteria, there are approximately 16 different strains. It can be found in many different environments: fermented foods and as normal microbiota. L.brevis is found in food such as sauerkraut and pickles. It is also one of the most common causes of beer spoilage. Ingestion has been shown to improve human immune function, and it has been patented several times. Normal gut microbiota L.brevis is found in human intestines, vagina and feces. L. brevis uses the glycolysis process to metabolize carbon sources by active transport, which moves material against the concentration gradient, normally this occurs is a movement from a high to low concentration. This pathway is used in probiotics and food preservation. There are significant vaginal bacteria that are found within the vagina and L. brevis is included in this microbiome, which is a collection of various bacteria. The bacteria collaborate on protecting the vagina and vaginal maintenance. Women of childbearing ages have a significant amount of L.brevis and this is normally found in a healthy vagina. For some illnesses or disruptions of the vagina this bacteria can be used in aiding to restore the microbiome. Most of the Lactobacillus species of bacteria have been found useful in preventing urinary tract infections. During normal childbirth, it appears that newborns after a period of days receive transmission of L. brevis from the mother. It appears that the transmission occurs through breast feeding or through natural child birth. In infants, this resistance is also helpful with protecting the gut against various bile and acids. Helicobacter pylori, which is a common gut pathogen in humans, studies have shown that certain strains of L.brevis are successful at combating this pathogen.Vaginosis is the most common form of bacterial infection this is commonly diagnosed as a yeast infection or trichomoniasis, which is a sexually transmitted parasite commonly acquired during intercourse. L.brevis along with Lactobacillus jensenii has been shown to produce high levels of hydrogen peroxide which may be able remediate the bacterial vaginosis pathogenesis. L. Brevis is a commonly used ingredient in pharmaceutical materials used to treat vaginosis. An evaluation of clue cells is one method of assessing vaginosis; this assessment is performed by mounting clue cells and vaginal discharge onto a slide then adding sodium chloride followed by a microscopic assessment which involves bacteria identification. Identified as a constituent of the oral microbiome by Human Oral Microbiome Database. Identified as constituent of vaginal microbiome. [PMID:23282177] This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072] |