Ruminococcus lactaris

RANK: Species

TAXONOMY: Terrabacteria group -> Firmicutes -> Clostridia -> Clostridiales -> Ruminococcaceae -> Ruminococcus -> Ruminococcus lactaris

OVERVIEW:

Ruminococcus lactaris (GenBank Accession Number for 16S rDNA gene: L76602) is a member of the Firmicutes division of the domain bacteria and has been isolated from human feces. The sequenced strain was obtained from ATCC (ATCC# 29176). This is from the Human Gut Microbiome Initiative. The available GenBank Accession Number is for the 16S rDNA gene of a related strain of Ruminococcus lactaris, not the sequenced strain.

This species has been identified as a resident in the human gastrointestinal tract based on the phylogenetic framework of its small subunit ribosomal RNA gene sequences.[PMC 4262072]

1

COGEM

COGEM released a comprehensive database of pathogenicity assessment of around 2575 bacterial species in 2011. The database ranks the pathogenicity of species on a scale of 1 to 4. Ruminococcus lactaris ranks 1 on this scale: The species or strain does not belong to a recognized group of disease-invoking agents in humans or animals and/or has an extended history of safe usage under conditions without any physical restrictions

Identified as a 'core species' of the human gut microbiome. [PMID: 23222524]

TAGS

Keystone	Core species	Type species	Pathogen	Dysbiosis associated	Flora/ commensal	Gut associated	Probiotic
Leanness	Obesity	Skin microbiome	Fecal distribution	Oral microbiome	Vaginal microbiome	Butyrate producer	Catalase producer
Histamine producer	Food fermenter	Amylolytic	Propionate producer	Nitrifying	Biofilm producer

INTERACTIONS ENHANCES Bacteroidales Bacteroides Odoribacter Anaerostipes Peptococcaceae INHIBITS Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Porphyromonas Prevotella Clostridium Clostridiales incertae sedis Clostridiales Family XIII. Incertae Sedis Blautia Coprococcus Dorea Lachnospiraceae Ruminococcaceae Ruminococcus Dialister Campylobacteraceae Erysipelotrichaceae INHIBITED BY Bifidobacterium Coriobacteriales Adlercreutzia Collinsella Bacteroidales Bacteroides Porphyromonadaceae Odoribacter Parabacteroides Porphyromonas Prevotella Rikenellaceae Alistipes Turicibacter Streptococcus Clostridiales Catabacteriaceae Clostridium Clostridiales incertae sedis Peptoniphilus Clostridiales Family XIII. Incertae Sedis Lachnospiraceae Blautia Lachnospiraceae Coprococcus Dorea Eubacterium Lachnobacterium Lachnospira Roseburia Lachnospiraceae Peptococcaceae Ruminococcaceae Ruminiclostridium Acetivibrio Eubacterium Faecalibacterium Oscillospira Ruminococcus Acidaminococcus Dialister Phascolarctobacterium Veillonella Rubrivivax Alcaligenaceae Oxalobacter Bilophila Desulfovibrio Campylobacteraceae Enterobacteriaceae Escherichia Erysipelotrichaceae Erysipelotrichaceae Holdemania Akkermansia	KEGG PATHWAYS CLUSTERS WITH	METABOLOMICS NUTRIENTS/ SUBSTRATES ENDPRODUCTS Lactate [parent] Formate [parent] Ethanol [parent] Succinate [parent] Acetate [parent] INHIBITED BY Momordia charantia [parent] Flaxseed [parent] High meat diet [parent] Proton-pump inhibitors (PPI) [parent] High fat diet [parent] ENHANCED BY Resistant starch (type II) [parent] Whole-grain barley [parent] Saccharomyces boulardii [parent] Navy bean (Cooked) [parent] Gynostemma pentaphyllum [parent] β-Glucan [parent] Resistant starch (type IV) [parent] Black Beans [parent] BIOTRANSFORMS Ginsenoside Rb1 [parent] Trimethylamine [parent] BIOTRANFORM Trimethylamine-N-oxide (TMAO) [parent]
ANTIBIOTIC RESISTANCE See Parent Genus (Ruminococcus)	BIOFILM FORMERS See Parent Genus (Ruminococcus)	COGEM PATHOGENICITY See Parent Genus (Ruminococcus)

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