 Help DocsDRUGGIE: Pharmacogenomics and adverse reactionsThe DRUGGIE app provides information on SNP-mediated pharmacogenomic interactions and potential adverse reactions. Getting around in DRUGGIE From the 'Informatics' link on the main menu, hover over 'Prescriptives' until a second menu list appears, then select DRUGGIE. You will then be presented with the default table, which shows 'everything' and is sorted by the 'Alert' column. Like most data-driven apps in Opus 23 Pro, DRUGGIE uses a filterable/sortable table to display its data. At the bottom of the data page window is a jump table that allows you to move from one page to the next. You can control how many rows to display by selecting an option from the 'Show' pull down menu. The default is 15. Filtering and sorting results  As you can see, there are over 16+ pages of drug data in DRUGGIE, which would make grinding through the data impractical. To deal with large amounts of data, DRUGGIE features a 'filterable' display. Type full or partial search terms into the search box at the upper left hand corner and DRUGGIE immediately displays only those results. Click on any column title to sort by that column. Click that column again to reverse the sort order. Click on the NOTEPAD icon to add or edit a note for that drug. If you want to create a note for the gene or SNP, click on it to open up its information pop-up, then press the 'Add/Edit' button. Clicking on the drug name will bring up information pop-up with the relevant PubMed abstract. The DRUGGIE table displays the following data by column: Drug, Implicated SNP, Gene, Defining (risk) allele, Client Genotype, Alert, and a description of the potential adverse reaction. Table rows that display the alert icon indicate that the client's genotype for that SNP is positive for a potential drug reaction. DRUGGIE only examines single-SNP pharmacogenomic associations. To examine multi-SNP pharmacogenomic outcomes, click on the 'Pharmacogenomics' category in the LUMEN app |
